$156.00
Overview
Melanotan II (MT-2) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH), developed at the University of Arizona alongside MT-1. It is shorter and more potent than MT-1, binding to a broader range of melanocortin receptors — MC1R, MC3R, and MC4R — producing a wider range of biological effects than pigmentation alone. MT-2 is also the source compound from which PT-141 (Bremelanotide) was derived, when researchers isolated its central sexual arousal mechanism into a dedicated compound. Understanding MT-2 is foundational to understanding the melanocortin peptide family as a whole.
What it does
MC1R activation triggers melanocytes to produce and distribute melanin — building pigmentation that accumulates over weeks and persists after the last dose due to melanin retention. MC3R activation influences appetite regulation and energy balance. MC4R activation in the hypothalamus drives centrally-mediated effects on sexual arousal — the same mechanism later refined in PT-141. MT-2 is highly dose-sensitive; results and side effects are closely correlated with dose titration.
Research areas
Skin pigmentation and melanin synthesis · Melanocortin receptor biology — MC1R, MC3R, MC4R · Sexual function and libido research · Appetite regulation and energy balance · Photoprotection research
Key facts
| Form | Lyophilised powder — requires reconstitution with bacteriostatic water |
| Storage | Lyophilised: -20°C, stable up to 2 years. Reconstituted: 2–8°C, use within 21 days |
| Purity | ≥99% — third-party COA verified, batch-specific documentation included |
| Important | Highly dose-sensitive — start low and titrate carefully. Monitor skin and moles during research |
For research use only. Not for human consumption. This product is not approved for human use by the FDA or any regulatory body.
