Overview
Selank is a synthetic peptide analogue of tuftsin, an endogenous immunomodulatory peptide, modified to enhance stability and extend biological activity within central nervous system research models. Developed in Russia as part of a broader class of regulatory peptides, Selank has been studied primarily for its effects on anxiety modulation, stress response, and cognitive stability. Unlike traditional anxiolytics, Selank does not act as a direct receptor agonist in the classical sense. Instead, it influences multiple neurotransmitter systems — particularly GABAergic, serotonergic, and dopaminergic pathways — through regulatory modulation rather than direct stimulation or suppression. This positions it as a system-balancing compound rather than a sedative agent.
What it does
Selank modulates GABA (gamma-aminobutyric acid) signalling — the primary inhibitory neurotransmitter in the brain — enhancing its regulatory effect on neural excitability without inducing sedation. This results in reduced anxiety-like behaviour in research models while maintaining cognitive clarity and functional performance. It also influences serotonin turnover and dopamine balance, contributing to improved mood stability and emotional regulation under stress conditions. Unlike benzodiazepine-class compounds, Selank does not demonstrate dependency-associated pathways in research models, and does not impair memory or cognitive function. Additionally, Selank has been shown to affect the expression of cytokines and immune signalling molecules, suggesting a link between its neurological effects and broader systemic regulation. Its combined mechanism supports both emotional stability and cognitive efficiency.
Research areas
Anxiety and stress-response research · GABAergic system modulation · Mood and emotional regulation studies · Cognitive stability and performance under stress · Neuroimmune interaction research · Memory and learning preservation
Key facts
| Form | Lyophilised powder — requires reconstitution with bacteriostatic water |
| Storage | Lyophilised: -20°C. Reconstituted: 2–8°C, use within 21 days |
| Purity | ≥99% — third-party COA verified, batch-specific documentation included |
| Origin | Synthetic analogue of tuftsin peptide |
| Note | Non-sedative profile in research models — does not impair cognition |
For research use only. Not for human consumption. This product is not approved for human use by the FDA or any regulatory body.
